abstract：OBJECTIVE:Peptic ulcers are the leading cause of upper gastrointestinal (GI) bleeding. The aim of this study was the evaluation of the recent clinical practice in drug therapy and endoscopic treatment of ulcer bleedings in Germany and to compare the results with the medical standard. METHODS:A structured questionnaire...

journal_title：Zeitschrift fur Gastroenterologie

authors： Maiss J,Schwab D,Ludwig A,Naegel A,Ende A,Hahn G,Zopf Y

更新日期：2010-02-01 00:00:00

abstract：:According to our knowledge and for the first time we refer about the combination therapy with gastric electric stimulation and injection of botulinus toxin into the pylorus at a patient with increased symptomatic diabetic gastroparesis for the first time. The prospectively documented gastroparesis-symptom-score improv...

journal_title：Zeitschrift fur Gastroenterologie

authors： Hummel M,Fuechtenbusch M

更新日期：2009-12-01 00:00:00

abstract：:Colorectal cancer is the most common cancer in Germany. The LebensBlicke foundation and it's supporting alliance have or many years, like others, been pushing information campaigns abour early detection measures and their chances for the general population. With the aid of the institute for public opinion research in ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Wuppermann D,Wuppermann U,Riemann JF

更新日期：2009-11-01 00:00:00

abstract：:Penile and scrotal swelling considered as metastatic Crohn's disease is described in a 23 years-old-man. Clinical features and therapeutic options of this rare manifeatation are reviewed. ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Kaess H,Nitsche U

更新日期：2009-09-01 00:00:00

abstract：:Measurement of chromogranin A (CgA) level in blood can be used to monitor neuroendocrine tumours. However CgA level may also be elevated in several other endocrine and non-endocrine diseases. Here, we report on a patient with an incidental left-sided adrenal tumour and elevated CgA level. Adrenalectomy did not confirm...

journal_title：Zeitschrift fur Gastroenterologie

authors： Wiedmann MW,Mössner J,Stumvoll M,Führer D

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Obscure gastrointestinal bleeding (OGIB) that cannot be established applying traditional endoscopic methods represents 5 % of all gastrointestinal bleedings. Earlier, in cases of recurrent, overt bleedings the surgeons had to perform a laparotomy "blind" without diagnosis. The aim of our retrospective study ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Kovács M,Pák P,Pák G,Oláh A,Rácz I

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Little is known about the similarities and differences in the clogging process of biliary and pancreatic stents. The aim of the study was to elucidate this process using scanning electron microscopy. MATERIALS AND METHODS:Scanning electron microscopy was performed in a consecutive series of 18 biliary and 1...

journal_title：Zeitschrift fur Gastroenterologie

authors： Weickert U,Zimmerling S,Eickhoff A,Riemann JF,Reiss G

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Capsule endoscopy is a common, pain-free diagnostic procedure for the small bowel. However, interpretation of the whole video recording is a time-consuming and costly procedure that can take up to 2 hours. The aim of the present study is two-fold: first to study the accuracy of capsule endoscopy analysis bet...

journal_title：Zeitschrift fur Gastroenterologie

authors： Riphaus A,Richter S,Vonderach M,Wehrmann T

更新日期：2009-03-01 00:00:00

abstract：:Biopsy diagnosis of early and highly differentiated liver tumors is difficult and complex. Modern pathology has met this challenge by several different means; elaborate morphological algorithms and novel immunohistological markers support the differential diagnosis of highly differentiated HCC and a new, predictive mo...

journal_title：Zeitschrift fur Gastroenterologie

authors： Longerich T,Schirmacher P

更新日期：2009-01-01 00:00:00

abstract：:Development of a megaesophagus with a sigmoid-shaped distal part in patients with achalasia--even in the course of successful myotomy with reduction of the resting pressure of the lower esophageal sphincter--is often the expression of an irreversible progression of the disease. Management of patients with end-stage ac...

journal_title：Zeitschrift fur Gastroenterologie

authors： Gockel I,Musholt TJ,Eckardt V,Mildenberger P,Müller H,Lang H

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Cystic liver lesions include hepatic echinococcosis as an important differential diagnosis, especially in patients from endemic countries. Serology might be false negative in a relevant percentage of the patients. Thus, modern clinical imaging techniques are the most important non-invasive means for making o...

journal_title：Zeitschrift fur Gastroenterologie

authors： Stock K,Hann von Weyhern C,Holzapfel K,Clevert DA,Schmid RM,Lersch C

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND AND AIM:Several gastrointestinal diseases are localised in the small bowel and are confirmed by duodenal biopsies upon upper gastrointestinal endoscopy. However, the clinical value of routine duodenal biopsies during endoscopy has not been satisfactorily defined and was assessed in the current study. METHOD...

journal_title：Zeitschrift fur Gastroenterologie

authors： Tischendorf JJ,Wopp K,Streetz KL,Bach J,Meyer M,Tischendorf S,Gassler N,Koch A,Geier A,Wasmuth HE,Trautwein C,Winograd R

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:In general, the rare SPT is a tumour of low malignancy predominantly affecting young women. The outcome after radical resection is favourable. In exceptional cases the tumour presents as solid pseudopapillary carcinoma (SPC) with typical malignant features and even metastases. Unresectable liver metastases c...

journal_title：Zeitschrift fur Gastroenterologie

authors： Foltys D,Moench C,Burck I,Hoppe-Lotichius M,Schad A,Teufel A,Heise M,Otto G

更新日期：2008-07-01 00:00:00

abstract：:Perianal and perineal ultrasound is an effective but rarely applied diagnostic modality. Transmural inflammation, fistula and abscesses in patients with inflammatory bowel disease can be delineated and perirectal tumours can be staged. The method is complementary to endorectal ultrasound. Also oblique transsphincteric...

journal_title：Zeitschrift fur Gastroenterologie

authors： Dietrich CF,Barreiros AP,Nuernberg D,Schreiber-Dietrich DG,Ignee A

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Radiation enteritis is a severe problem in patients receiving irradiation of the abdomen or pelvis in the course of cancer treatment. Nevertheless, there is a lack of standardised strategies for medical prevention and therapy. MATERIALS AND METHODS:A PubMed based literature search was performed to address t...

journal_title：Zeitschrift fur Gastroenterologie

authors： Zimmerer T,Böcker U,Wenz F,Singer MV

更新日期：2008-05-01 00:00:00

abstract：:Endoscopic retrograde cholangiography (ERC) after Roux-en-Y reconstruction and modified BII surgery or duodenopancreatectomy is considerably more difficult than ERC under normal anatomic conditions. If the common bile in the afferent loop cannot be reached by a common lateral-viewing duodenoscope because of excessive ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Fähndrich M,Sandmann M,Heike M

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:5- Aminosalicylic acid (5-ASA) is metabolised in colonic mucosa by N-acetyltransferase 1 (NAT1). Common genetic polymorphisms in this enzyme result in rapid or slow acetylation. 5-ASA treatment causes side effects in up to 10 % of patients with ulcerative colitis (UC). We therefore determined genetic variati...

journal_title：Zeitschrift fur Gastroenterologie

authors： Hausmann M,Paul G,Menzel K,Brunner-Ploss R,Falk W,Schölmerich J,Herfarth H,Rogler G

更新日期：2008-03-01 00:00:00

abstract：:We report on a 43-year-old patient presenting to the emergency department with acute abdominal pain the source of which turned out to be acute hemorrhagic jejunal infarction due to portal and mesenteric vein occlusion with no apparent cause. In spite of a lacking history of hereditary thrombophilic risk factors, furth...

journal_title：Zeitschrift fur Gastroenterologie

authors： Garlipp B,Gerhardt U,Linke J,Arlt G

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Achalasia in childhood is rare, also the etiology and the pathogenesis of the early onset ort he disease is practically unknown. Little is known about the neuropathological changes in structure of the esophageal wall in non-hereditary, sporadic achalasia in children and ist differentiation to that in adults....

journal_title：Zeitschrift fur Gastroenterologie

authors： Bohl J,Gockel I,Sultanov F,Eckardt V,Junginger T

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Esophageal dilatation is performed for the treatment of anatomic and sometimes functional narrowing of the esophageal lumen caused by a variety of benign and malignant conditions. Esophageal perforation is the major complication associated with endoscopic dilatation. AIM:The object of this study was to asse...

journal_title：Zeitschrift fur Gastroenterologie

authors： Fry LC,Mönkemüller K,Neumann H,Schulz HU,Malfertheiner P

更新日期：2007-11-01 00:00:00

abstract：AIM:The objective of this study was to assess the efficacy and safety of the phytopharmacon STW 5 versus metoclopramide in functional dyspepsia. METHODS:A retrolective, epidemiological cohort study with parallel groups in 23 randomised centres where both drugs were used routinely was performed. The main outcome variab...

journal_title：Zeitschrift fur Gastroenterologie

authors： Raedsch R,Hanisch J,Bock P,Sibaev A,Vinson B,Gundermann KJ

更新日期：2007-10-01 00:00:00

abstract：:This guideline provides evidence-based key recommendations for diagnosis and therapy of gallstones and upgrades version 2000. It was developed by an interdisciplinary team of gastroenterologists, surgeons, radiologists, geneticists, external comparative quality assurance and patient support groups under the auspices o...

journal_title：Zeitschrift fur Gastroenterologie

authors： Lammert F,Neubrand MW,Bittner R,Feussner H,Greiner L,Hagenmüller F,Kiehne KH,Ludwig K,Neuhaus H,Paumgartner G,Riemann JF,Sauerbruch T,Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten.,Deutschen Gesellschaft fü

更新日期：2007-09-01 00:00:00

abstract：:An HIV-1 seronegative man presented with odynophagia, dysphagia, diarrhea, tenesmus and a 50-lb weight loss. A large esophageal ulcer and a rectal fissure were identified endoscopically. Stool samples and biopsy specimens from the esophageal ulcer, duodenum, colon and rectum were negative for pathogens. Seronegative A...

journal_title：Zeitschrift fur Gastroenterologie

authors： Mönkemüller K,Fry LC,Decker JM,Rickes S,Smith PD

更新日期：2007-08-01 00:00:00

abstract：:Ultrasonography has become widely accepted as a diagnostic tool for gastrointestinal diseases. It not only assesses the lumen but more importantly also the wall and the surrounding structures of the stomach and bowel. Furthermore, functional processes (peristalsis, blood flow) can be visualised and provide important i...

journal_title：Zeitschrift fur Gastroenterologie

authors： Nuernberg D,Ignee A,Dietrich CF

更新日期：2007-07-01 00:00:00

abstract：:This document contains the guidelines of the German Societies of Neurogastroenterology and Motility, Gastroenterology (committee for proctology), Abdominal Surgery (coloproctology working group), and Coloproctology for anorectal manometry in adults. Recommendations are given about technical notes, study preparation (e...

journal_title：Zeitschrift fur Gastroenterologie

authors： Pehl C,Enck P,Franke A,Frieling T,Heitland W,Herold A,Hinninghofen H,Karaus M,Keller J,Krammer HJ,Kreis M,Kuhlbusch-Zicklam R,Mönnikes H,Münnich U,Schiedeck T,Schmidtmann M,German Society for Neurogastroenterology and Mot

更新日期：2007-05-01 00:00:00

abstract：:Liver fibrosis is the final common pathway in a variety of liver diseases. To model liver fibrosis in mice is important as mechanisms not only of fibrogenesis, but also of fibrolysis, need to be clearly defined. Also, small rodents present a possibility to test potential treatments in vivo. Today, there are several mo...

journal_title：Zeitschrift fur Gastroenterologie

authors： Weiler-Normann C,Herkel J,Lohse AW

更新日期：2007-01-01 00:00:00

abstract：:Fluorouracil-associated cardiotoxic adverse events represent a relevant but underestimated problem in 5-fluorouracil treatment. After right hemicolectomy for adenocarcinoma of the rightsided colonic flexure a 59-year old patient was referred to our hospital for adjuvant chemotherapy according to MOSAIC-protocol with o...

journal_title：Zeitschrift fur Gastroenterologie

authors： Gundling F,Fuchs M,Nowak L,Antoni D,Hoffmann E,Schepp W

更新日期：2006-09-01 00:00:00

abstract：:Non-resectable cholangiocarcinoma and gallbladder carcinoma have a poor prognosis. In addition to the general aspects of "best supportive care", biliary drainage is an important part of the palliative treatment of patients with malignant biliary stenosis. Photodynamic therapy has led to an improved median survival in ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Klebl F,Endlicher E,Kullmann F

更新日期：2006-07-01 00:00:00

abstract：:A 62-year-old lady presented with fever and abdominal pain. History revealed cholecystectomy two years ago due to cholecystolithiasis, complicated by perforation of the common bile duct, leading to hepaticojejunostomy, jejunocholedochostomy, endoscopic retrograde insertion of two plastic stents and percutaneous draina...

journal_title：Zeitschrift fur Gastroenterologie

authors： Zuber-Jerger I,Schoelmerich J,Kullmann F

更新日期：2006-04-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) commonly is associated with chronic inflammatory bowel disease (CIBD) and usually is considered to be stable and benign. However, NAFLD -- and in particular its subset, non-alcoholic steatohepatitis (NASH) -- may lead to progressive liver disease. Moreover, NAFLD sensitizes th...

journal_title：Zeitschrift fur Gastroenterologie

authors： Canbay A,Bechmann LP,Best J,Jochum C,Treichel U,Gerken G

更新日期：2006-03-01 00:00:00

abstract：:Common causes of chronically elevated serum liver enzymes include fatty liver disease, chronic viral hepatitis, autoimmune hepatitis, or hereditary metabolic disorders. Adrenocortical insufficiency can also cause elevated liver enzymes. Since 1990 only 11 cases have been reported. We here report a 52-year-old man with...

journal_title：Zeitschrift fur Gastroenterologie

authors： Gurakuqi GC,Stadlbauer V,Stepan V,Warnkross H,Trauner M

更新日期：2006-02-01 00:00:00

abstract：:The liver is an organ with unique immune regulatory potential. This review highlights the experimental evidence for the involvement of hepatic cell populations in the induction of oral tolerance. Although immune tolerance towards oral antigens is mainly induced in the gastrointestinal tract within gut associated lymph...

journal_title：Zeitschrift fur Gastroenterologie

authors： Knolle PA

更新日期：2006-01-01 00:00:00

abstract：:In spite of modern diagnostic possibilities, the diagnosis of celiac disease is still challenging for the physician. This is due to the great variability of the clinical presentation. Nowadays, the classical symptoms like diarrhea, weight loss and abdominal pain are seen less often. It has become evident that celiac d...

journal_title：Zeitschrift fur Gastroenterologie

authors： Holtmeier W

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Endoscopic stenting with self-expanding metal stents (SEMS) has proved to be an efficient palliative endoscopic therapy option in treating malignant dysphagia. Different types of SEMS have been examined previously in small randomized clinical trials. METHODS:A total of 150 consecutive patients (from 1/1995-...

journal_title：Zeitschrift fur Gastroenterologie

authors： Eickhoff A,Hartmann D,Jakobs R,Weickert U,Schilling D,Eickhoff JC,Riemann JF

更新日期：2005-10-01 00:00:00

abstract：:Gastrointestinal stromal tumours (GIST) occur mostly as sporadic solitary lesions involving the tubular GI tract and are only rarely associated with other benign or malignant neoplasms or occur as part of a multi-neoplastic disease as in the setting of Carney's triad and von Recklinghausen's disease. We analysed a tot...

journal_title：Zeitschrift fur Gastroenterologie

authors： Agaimy A,Wuensch PH

更新日期：2005-09-01 00:00:00

abstract：:The oesophagus, stomach and pancreas are primary target organs for ethanol-related diseases. In the oesophagus and stomach, ethanol induces motility disorders and mucosal lesions that are dose-dependent and reversible under acute conditions. Chronic consumption of alcohol causes a significant increase in the risk for ...

journal_title：Zeitschrift fur Gastroenterologie

authors： Siegmund SV,Singer MV

更新日期：2005-08-01 00:00:00

abstract：:Patients with portal hypertension may develop pulmonary complications such as hepatopulmonary syndrome (HPS) or portopulmonary hypertension (PPHT). PPHT is defined as elevated pulmonary pressure, elevated pulmonary vascular resistance, a normal pulmonary capillary wedge pressure, and portal hypertension in the absence...

journal_title：Zeitschrift fur Gastroenterologie

authors： Halank M,Miehlke S,Kolditz M,Hoeffken G

更新日期：2005-07-01 00:00:00

abstract：:We present the case of a primary malignant esophageal melanoma arising in a 75-year-old male, initially diagnosed as anaplastic squamous cell carcinoma. After resection of the tumor, histological work-up was indicative of a marked morphological heterogeneity, resembling a focally amelanotic primary malignant melanoma....

journal_title：Zeitschrift fur Gastroenterologie

authors： Heidemann J,Lebiedz P,Herbst H,Spahn TW,Domagk D,Domschke W,Kucharzik T

更新日期：2005-06-01 00:00:00

abstract：:Probiotics are defined as living micro-organisms which, when administered in large amounts, confer a health benefit on the host. The use of probiotics in the therapy of infectious bowel diseases as well as maintaining remission of ulcerative colitis and in pouchitis is evidence-based. Also, in several studies proof co...

journal_title：Zeitschrift fur Gastroenterologie

authors： Krammer HJ,Schlieger F,Harder H,Franke A,Singer MV

更新日期：2005-05-01 00:00:00

abstract：INTRODUCTION:Gastroesophageal reflux (GER) is the main risk factor for the development of adenocarcinoma of the esophagus (AC). The aim of our study was to evaluate symptoms of patients with AC to identify those patients with a high risk for this tumour. PATIENTS AND METHODS:117 consecutive patients with known AC were...

journal_title：Zeitschrift fur Gastroenterologie

authors： Leers J,Bollschweiler E,Hölscher AH

更新日期：2005-03-01 00:00:00